Pengajian peringkat Menengah Atas di SMK Tinggi Kluang terbahagi kepada beberapa aliran mengikut subjek yang ditawarkan. Bermula di Tingkatan 4, terdapat 5 aliran yang ditawarkan, iaitu Sains Tulen (ST), Sains + Sains Komputer (RSK), Sains + Perniagaaan (PS), Sains +Akaun (PA) dan Sains Kemanusiaan (SK). Setiap kelas diwajibkan untuk mengambil matapelajaran teras dan matapelajaran lain dibahagikan mengikut aliran yang dipilih. Pentaksiran yang dibuat adalah sejajar dengan kehendak Kementerian Pendidikan Malaysia (KPM) iaitu peperiksaan, Pentaksiran Bilik Darjah (PBD), pentaksiran kokurikulum (PAJSK) dan pentaksiran psikometrik.

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Upper Secondary level studies at SMK Tinggi Kluang are divided into several streams according to the subjects offered. Starting in Form 4, there are 5 streams offered, namely Pure Science (ST), Science + Computer Science (RSK), Science + Business (PS), Science + Accounts (PA) and Humanities (SK). Each class is required to take core subjects and other subjects are divided according to the chosen stream. The assessment is in line with the requirements of the Malaysian Ministry of Education (KPM) which are examinations, Classroom-Based Assessment (PBD), co-curricular assessment (PAJSK) and psychometric assessment.

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